Schizophrenia linked with abnormal immune response to Epstein-Barr virus
New research shows that people in the study with schizophrenia also have higher levels of antibodies against the Epstein-Barr virus (EBV), a herpes virus that causes infectious mononucleosis, so-called...
View ArticleHerpes viruses and tumors evolved to learn how to manipulate the same ancient...
Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors have been found to manipulate, Mount Sinai researchers have shown...
View ArticleViral communications hacking boosts Leishmania infections
New research has found that a virus infecting the Leishmania parasite spreads by exploiting a mechanism used for cell-to-cell communication, a discovery that could pave the way to new vaccines against...
View ArticleDormant viruses activate during spaceflight
Herpes viruses reactivate in more than half of crew aboard Space Shuttle and International Space Station missions. While only a small proportion develop symptoms, virus reactivation rates increase with...
View ArticleAging baby boomers push sky high incidence of shingles of the eye
More Americans are being diagnosed with eye complications of shingles, but older adults can call the shots on whether they are protected from the painful rash that can cost them their eyesight.
View ArticleProbiotic-derived molecule may suppress fatal brain inflammation, preclinical...
The existence of certain microorganisms in your gut may bolster the immune system's ability to fend off a herpes viral attack that can cause fatal brain inflammation.
View ArticleNew findings could lead to improved vaccinations against sexually transmitted...
In a new study, researchers show how skin vaccination can generate protective CD8 T-cells that are recruited to the genital tissues and could be used as a vaccination strategy for sexually transmitted...
View ArticleChickenpox vaccination lowers risk of pediatric shingles
A study of more than 6 million children showed routine varicella vaccine considerably lessened likelihood of painful shingles disease.
View ArticleTaking the 'killer' out of natural killer cells
The virus responsible for chickenpox and shingles employs a powerful strategy of immune evasion, inhibiting the ability of natural killer cells to destroy infected cells and produce molecules that help...
View Article'Is it time for another contraception revolution?'
In an effort to protect the planet and preserve its natural treasures for future generations, another contraception revolution that provides options for populations not currently being served by modern...
View ArticleCan a combination immune therapy reduce genital herpes outbreaks?
Investigators have shown that the combination of a vaccine and a medicated cream is a promising strategy to dramatically reduce the recurrence of genital herpes.
View ArticleCharcoal-based drug delivery system improves efficacy of common herpes drug
A study has found that combining acyclovir -- a commonly prescribed topical herpes medication -- with particles of activated carbon improves efficacy of the drug.
View ArticleNew vaccine prevents herpes in mice, guinea pigs
A novel vaccine protected almost all mice and guinea pigs exposed to a new herpes virus. This may lead to the vaccine being tested in human studies.
View ArticleFighting the herpes virus
Researchers have used single-cell RNA sequencing to better understand the viral infections.
View ArticleDiscovery reveals mechanism that turns herpes virus on and off
New research has identified a new mechanism that plays a role in controlling how the herpes virus alternates between dormant and active stages of infection.
View ArticleMS linked to variant of common herpes virus
Researchers have developed a new method to separate between two different types of a common herpes virus (HHV-6) that has been linked to multiple sclerosis. By analyzing antibodies in the blood against...
View ArticleHerpes's Achilles heel
Scientists have used the gene-editing tool CRISPR-Cas9 to disrupt both latent reservoirs of the herpes simplex virus and actively replicating virus in human fibroblast cells. Experiments pinpoint weak...
View ArticleAre herpes virus infections linked to Alzheimer's disease?
Researchers refute the link between increased levels of herpes virus and Alzheimer's disease.
View ArticleUnique new antiviral treatment made using sugar
New antiviral materials made from sugar have been developed to destroy viruses on contact and may help in the fight against viral outbreaks. This new development from a collaborative team of...
View ArticleCancer side-effects: Sweet nanoparticles trick kidney
Researchers engineer tiny particles with sugar molecules to prevent side effect in cancer therapy.
View ArticleCurcumin is the spice of life when delivered via tiny nanoparticles
For years, curry lovers have sworn by the anti-inflammatory properties of turmeric, but its active compound, curcumin, has long frustrated scientists hoping to validate these claims with clinical...
View ArticleHerpes virus decoded
The genome of the herpes simplex virus 1 was decoded using new methods. Hundreds of previously unknown gene products were found. The virus causes lip herpes, but can also be life-threatening.
View ArticleUncovering the Achilles heel of viruses
New research identifies how viruses avoid the body's immune system and cause infections and diseases.
View ArticleAntiviral method against herpes paves the way for combating incurable viral...
Researchers have discovered a new method to treat human herpes viruses. The new broad-spectrum method targets physical properties in the genome of the virus rather than viral proteins, which have...
View ArticleNew gene therapy approach eliminates at least 90% latent herpes simplex virus 1
Infectious disease researchers have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes. In animal models, the findings show at least a 90 percent...
View ArticleKey role of immune cells in brain infection
Researchers have identified the specific type of immune cell that induces brain inflammation in herpes simplex virus (HSV) encephalitis. Crucially, they have also determined the signalling protein that...
View ArticleVaccine shows promise against herpes virus
A genetically edited form of a herpes simplex virus has outperformed a leading vaccine candidate in a new study. When challenged with a virulent strain of the sexually transmitted HSV-2, vaccinated...
View ArticleCold sores: Discovery reveals how stress, illness and even sunburn trigger...
The finding could lead to new ways to prevent cold sores and herpes-related eye disease from reoccurring, the researchers report.
View ArticleHidden link between cellular defense systems
Researchers have discovered that heparanase, HPSE, a poorly understood protein, is a key regulator of cells' innate defense mechanisms.
View ArticleDifferences in herpes virus symptoms may relate to variations in strain gene...
Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study finds that these differences could be due...
View ArticleChronic viral infections can have lasting effects on human immunity, similar...
Research suggests that chronic viral infections have a profound and lasting impact on the immune system in ways that are similar to those seen during aging. Using systems immunology and artificial...
View ArticleMicroscopy deep learning predicts viral infections
When viruses infect cells, changes in the cell nucleus occur, and these can be observed through fluorescence microscopy. Using fluorescence images from live cells, researchers have trained an...
View ArticleHow herpes checks into the nervous system for life
More than half of U.S. adults are carriers of HSV1 (herpes simplex virus type 1) which hibernates in the peripheral nervous system and can never be eradicated. A new study has uncovered herpes' sneaky...
View ArticleHow oral bacteria suppress protection against viral growth
Researchers have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth. They also found that oral bacteria can suppress...
View ArticleStudy identifies new way to attack herpesviruses
A new study has opened the door to a new approach to attacking herpesviruses. The study demonstrated that targeting 2 metal ion-dependent enzymes of human herpesviruses with 2 compounds, AK-157 and...
View ArticleHow herpesviruses awaken
Dormant herpesviruses induce their reactivation via a previously unknown cellular mechanism mediated by a viral microRNA.
View ArticleCornea T cells protect eyes from viral infections, researchers discover
The cornea -- the transparent protective outer layer of the eye critical to helping us see -- produces a delicate and limited immune response to fight infections without damaging our vision, according...
View ArticleCommon viruses may be triggering the onset of Alzheimer's disease
Two common viruses lie dormant in neurons -- herpes simplex virus (HSV), and varicella zoster virus (VZV). Lab models of the human brain show that activation or re-infection of VZV can trigger...
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View ArticleAI model helps atopic dermatitis patients diagnose complications and...
Atopic dermatitis skin lesions and the lesions produced by infectious complications of the disease look so similar that it makes it impossible for patients to spot the difference and know when to visit...
View ArticleCommon infections linked to poorer cognitive performance in middle-aged and...
A new study found that signs of common infections in a sample of middle-aged and older adults were associated with poorer performance on a test of global cognitive function.
View ArticleHerpes study adds to understanding of viral reinfections, how to potentially...
A new study on herpes infections of the eye helps shed light on the question of viral reinfections by identifying a key protein involved in viral reinfections that could be targeted by antiviral drugs.
View ArticleStudying herpes encephalitis with mini-brains
The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists.
View ArticleKeeping herpes in check
Herpes is not only unpleasant but it can, in some cases, also have dangerous complications and life-threatening consequences. A research team has now introduced a completely new approach for treating...
View ArticleDouble risk of dementia after mouth ulcer virus
People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected. A new study confirms previous research on...
View ArticleIn fight against brain pathogens, the eyes have it
The eyes have been called the window to the brain. It turns out they also serve as an immunological barrier that protects the organ from pathogens and even tumors, researchers have found. In a new...
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